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Development of new chiral phosphine-salen type ligands and their application in the Cu(I)-catalyzed enantioselective Henry reaction

✍ Scribed by Jia-Jun Jiang; Min Shi


Book ID
108284232
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
195 KB
Volume
18
Category
Article
ISSN
0957-4166

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Synthesis of Chiral 1,3-Diamines Derived
✍ Dr. Koichi Kodama; Kazuyuki Sugawara; Prof. Takuji Hirose πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 438 KB πŸ‘ 1 views

## Abstract In this study, 13 different chiral 1,3‐diamines were synthesized from (βˆ’)‐__cis__‐2‐benzamidocyclohexanecarboxylic acid. They were successfully applied as ligands in the Cu‐catalyzed asymmetric Henry reaction between benzaldehyde and nitromethane. It was confirmed that the enantioselect