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Development of LC/MS/MS Methods for Cocktail Dosed Caco-2 Samples Using Atmospheric Pressure Photoionization and Electrospray Ionization

✍ Scribed by Hakala, Kati S.; Laitinen, Leena; Kaukonen, Ann Marie; Hirvonen, Jouni; Kostiainen, Risto; Kotiaho, Tapio


Book ID
120063685
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
174 KB
Volume
75
Category
Article
ISSN
0003-2700

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## Abstract A highly sensitive and specific LC‐MS/MS method has been developed and validated for the estimation of torcetrapib (TTB) with 100 Β΅L hamster/dog plasma using DRL‐16126 as an internal standard (IS). The API‐4000 Q Trap LC‐MS/MS was operated under multiple‐reaction monitoring mode using t