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Development of hydrocortisone succinic acid/and 5-fluorouracil/chitosan microcapsules for oral and topical drug deliveries

โœ Scribed by Pik-Ling Lam; Kenneth Ka-Ho Lee; Raymond Siu-Ming Wong; Gregory Yin Ming Cheng; Shuk Yan Cheng; Marcus Chun-Wah Yuen; Kim-Hung Lam; Roberto Gambari; Stanton Hon-Lung Kok; Chung-Hin Chui


Book ID
113496787
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
723 KB
Volume
22
Category
Article
ISSN
0960-894X

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โœ Mohammad Reza Saboktakin; Roya M. Tabatabaie; Abel Maharramov; Mohammad Ali Rama ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 149 KB

The main aim of this research was to develop and evaluate a multiparticulate system of Ac-poly(amidoamine)(PAMAM)(G4)-chitosan (CS) hydrogels exploiting pH-sensitive and specific biodegradability properties for colon-targeted delivery of 5-aminosalicylic acid (5-ASA). All formulations were evaluated