𝔖 Bobbio Scriptorium
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Development of Functional Human Monoclonal Single-Chain Variable Fragment Antibody Against HIV-1 from Human Cervical B Cells

✍ Scribed by Berry, Jody D.; Rutherford, John; Silverman, Gregg J.; Kaul, Rupert; Elia, Marikka; Gobuty, Sarah; Fuller, Roberta; Plummer, Francis A.; Barbas, Carlos F.


Book ID
120361127
Publisher
Mary Ann Liebert
Year
2003
Tongue
English
Weight
360 KB
Volume
22
Category
Article
ISSN
1536-8599

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## Background The ability of cytosine deaminase (CD) to convert the antifungal agent 5-fluorocytosine (5-FC) into one of the most potent and largely used anticancer compound such as 5-fluorouracil (5-FU) raised considerable interest in this enzyme to model gene or antibody – directed enzyme-prodrug