## Electrospray ionisation (ESI) mass spectrometry combined with collision-induced decomposition of ions given by captopril, lisinopril and enalaprilat, angiotensin-converting enzyme (ACE) inhibitors, has been used to characterise these compounds. As expected, the ESI mass spectra are characterised
Development of Domain-Selective Angiotensin I-Converting Enzyme Inhibitors
โ Scribed by Pierre Redelinghuys; Aloysius T. Nchinda; Edward D. Sturrock
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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Self carbohydrate-mediated dimerization of glycoprotein angiotensin-converting enzyme (ACE) was demonstrated. The dimerization was studied in the reverse micelle experimental system as a model of biomembrane situation. Asialo-ACE or agalacto-ACE was able to form a dimer, whereas deglycosylated ACE a
## Abstract ## Objectives/Hypothesis: To develop and validate a clinical algorithm for management of patients with angiotensinโconverting enzyme inhibitorโinduced angioedema (AIIA). ## Study Design: Prospective cohort observational study. ## Methods: Over 1 year, 40 patients with AIIA were eva
## Abstract ## BACKGROUND. Angiotensin Iโconverting enzyme (ACE) inhibitors, angiotensin II antagonists, and the ACE insertion/deletion (I/D) gene polymorphism all influence serum angiotensin II action. Because angiotensin II levels have been associated with cancer, the objective of the current ep