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Development of Dickie's small eye, a mutation in the house mouse

✍ Scribed by Karl Theiler; Don S. Varnum; Leroy C. Stevens

Publisher
Springer
Year
1979
Tongue
English
Weight
708 KB
Volume
155
Category
Article
ISSN
0340-2061

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✦ Synopsis

A new semidominant mutation in the laboratory mouse, Dickie's small eye (Dey), is described. It is localized on chromosome 2. Heterozygotes show reduced body size, small eyes with coloboma, small or lacking lens with cataract, abnormal folding of the retina and reduction of the pigment layer. The anterior chamber is usually missing. Homozygotes apparently die early in pregnancy.

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