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Development of defined and feeder-free media for the expansion of hematopoietic stem cells

✍ Scribed by Young-Joo Jeon; Yong-Soo Choi; Ji-Hae Song; Bu-Young Park; Jong-Il Kim; Mi-Eun Kong; Hyung-jin Jeon; Dong-Il Kim


Book ID
118473235
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
56 KB
Volume
136
Category
Article
ISSN
0168-1656

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Expansion of hematopoietic stem cells (HSCs) from cord blood is highly desired for treatment and transplantation of adult patients for hematologic diseases. For efficient proliferation of HSCs, CD34(+) cells from cord blood were co-cultured with microencapsulated murine stromal cells (HESS-5) or imm