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Development of brainstem 5-HT 1A receptor-binding sites in serotonin-deficient mice

✍ Scribed by Massey, Caitlin A.; Kim, Gloria; Corcoran, Andrea E.; Haynes, Robin L.; Paterson, David S.; Cummings, Kevin J.; Dymecki, Susan M.; Richerson, George B.; Nattie, Eugene E.; Kinney, Hannah C.; Commons, Kathryn G.

Book ID
120652147
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
612 KB
Volume
126
Category
Article
ISSN
0022-3042

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A loss of endocrine and neurotransmitter system interactions, including corticosterone regulation of 5-HT 1A receptors, may underlie the age-related deficits in the hypothalamic-pituitary-adrenal (HPA) axis including adapting to stress. In this study, female Fischer 344 rats, (ages 3, 13, and 18 mon