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Development of biomarkers of human exposure to carcinogens: the example of DNA-protein cross-links

✍ Scribed by Toniolo, Paolo; Taioli, Emanuela

Book ID
123520884
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
351 KB
Volume
77
Category
Article
ISSN
0378-4274

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Levels of DNA strand breaks and DNA-protein cross-links (DPCs) were measured using the alkaline elution assay in normal human skin fibroblasts irradiated with 0-200 J m-2 of 254 nm UV radiation and incubated for 0-24 h. On incubation, the yields of both single-strand breaks (SSBs) and DPCs increased