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Development of an HPLC Method for Determination of Related Impurities in Prilocaine Substance

✍ Scribed by Janina Sroka-Markovic; Linda Johansson; Magnus B. O. Andersson; Ingrid Granelli

Book ID
113059282
Publisher
Springer
Year
2012
Tongue
English
Weight
403 KB
Volume
75
Category
Article
ISSN
0009-5893

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## Abstract A novel stability‐indicating high‐performance liquid chromatographic (HPLC) method was developed and validated for assay and determination of impurities of emtricitabine in drug substance. Emtricitabine was found to be degraded under acidic, alkaline, and oxidative stress conditions and