## Abstract The liquid chromatographic separation of permethrin enantiomers on chiral Ξ²βcyclodextrinβbased stationary phase has been investigated. All four enantiomers are obtained by using simple methanol and water mobile phase, under gradient mode. The method was optimized and validated. The rela
Chiral HPLC method for chiral purity determination of paroxetine drug substance
β Scribed by Janusz Zukowski; Malcolm Brightwell; Vern de Biasi
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 94 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0899-0042
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π SIMILAR VOLUMES
O-Nitromandelic acid, easily prepared from either enantiomer of mandelic acid, has been used as a chiral solvating agent for the determination of enantiomeric purity of several diamine derivatives and other compounds using 1 H NMR spectroscopy.
An extensive study of the behavior of three chiral stationary phases (CSP) used in liquid chromatography (LC) is presented for the stereoselective determination of methadone. The following chromatographic columns were selected: a cellulose, Chiralcel OJ; a modified cyclodextrin, Cyclobond I 2000 RSP