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Development of an automatic solid phase extraction and liquid chromatography mass spectrometry method by using a monolithic column for the analysis of Cyclosporin A in human plasma

✍ Scribed by Covadonga Alvarez; Irving W. Wainer

Book ID
116903705
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
257 KB
Volume
79
Category
Article
ISSN
0039-9140

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## Abstract A rapid, sensitive and selective liquid chromatography–tandem spectrometry method was developed and validated for determination of paeoniflorin in rat plasma using geniposide as the internal standard. The samples were pretreated with solid‐phase extraction using Extract‐Clean™ cartridge