✦ LIBER ✦

Development of a Practical Synthesis of DPP IV Inhibitor LY2497282 †

✍ Scribed by Yu, Hannah; Richey, Rachel N.; Stout, James R.; LaPack, Mark A.; Gu, Ruilin; Khau, Vien V.; Frank, Scott A.; Ott, Joel P.; Miller, Richard D.; Carr, Michael A.; Zhang, Tony Y.

Book ID: 126133855
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 401 KB
Volume: 12
Category: Article
ISSN: 1083-6160
DOI: 10.1021/op700235c

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Preparation of Saxagliptin, a Novel DPP-

Preparation of Saxagliptin, a Novel DPP-IV Inhibitor

✍ Savage, Scott A.; Jones, Gregory S.; Kolotuchin, Sergei; Ramrattan, Shelly Ann; 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 279 KB

Proline-Catalyzed, Asymmetric Mannich Re

Proline-Catalyzed, Asymmetric Mannich Reactions in the Synthesis of a DPP-IV Inhibitor

✍ Janey, Jacob M.; Hsiao, Yi; Armstrong, Joseph D. 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 52 KB

Design, synthesis and primary activity o

Design, synthesis and primary activity of thiomorpholine derivatives as DPP-IV inhibitors

✍ Bei Han; Jing Long Liu; Yi Huan; Peng Li; Qi Wu; Zi Yun Lin; Zhu Fang Shen; Da L 📂 Article 📅 2012 🏛 Chinese Electronic Periodical Services 🌐 English ⚖ 429 KB

Efficient synthesis of sitagliptin phosp

Efficient synthesis of sitagliptin phosphate, a novel DPP-IV inhibitor, via a chiral aziridine intermediate

✍ Pan, Xianhua; Li, Xiaojun; Lu, Qingling; Yu, Wansheng; Li, Weijin; Zhang, Qunhui 📂 Article 📅 2013 🏛 Elsevier Science 🌐 French ⚖ 576 KB

Structural studies of a bifunctional inh

Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV

✍ Oefner, Christian ;Pierau, Sabine ;Schulz, Henk ;Dale, Glenn E. 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 528 KB

Neutral endopeptidase (NEP) is the major enzyme involved in the metabolic inactivation of a number of bioactive peptides including the enkephalins, substance P, endothelin, bradykinin and atrial natriuretic factor, as well as the incretin hormone glucagon-like peptide 1 (GLP-1), which is a potent st

A Practical Synthesis of Multitargeted A

A Practical Synthesis of Multitargeted Antifolate LY231514

✍ Barnett, Charles J.; Wilson, Thomas M.; Kobierski, Michael E. 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 107 KB