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Development of a new method for testing strength of cells against fluid shear stress

✍ Scribed by N. Shiragami


Publisher
Springer
Year
1994
Tongue
English
Weight
416 KB
Volume
10
Category
Article
ISSN
1615-7605

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✦ Synopsis


A new method for testing the strength of cells against fluid shear stress by using a long capillary column was proposed. The trajectories of cells in the column were simulated by introducing the Brownian motion model. The Brownian motion was performed by the generation of random numbers. The mean exposure time to shear stress and the mean shear stress acting on the surface of cells were discussed by the result of computer simulation. The mean shear stress acting on the surface of cells flowing in the capillary column was estimated as 4/3-fotd of the shear stress at the column walt provided that the ratio of the cell radius to the column radius does not exceed 0.08. The effectiveness of this new method for testing the strength of cells against fluid shear stress was shown.


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