Pharmacokinetic–pharmacodynamic modeling
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Evelyn D. Lobo; Joseph P. Balthasar
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Article
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2003
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John Wiley and Sons
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English
⚖ 138 KB
The prediction of chemotherapeutic efficacy is complicated by "protocol dependencies" in dose-effect and dose-toxicity relationships. It has been proposed that pharmacokinetic-pharmacodynamic mathematical models may allow characterization of chemotherapeutic protocol dependencies, and may facilitate