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Development of a continuous assay for the measurement of tissue factor procoagulant activity on intact cells

✍ Scribed by Caldwell, Jennifer A; Dickhout, Jeffrey G; Al-Hashimi, Ali A; Austin, Richard C

Book ID
109885541
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
490 KB
Volume
90
Category
Article
ISSN
0023-6837

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## Abstract ## Background The use of retroviral vectors has shown an actual clinical benefit in a few inherited diseases. However, the occurrence of cases of leukemia after the X‐SCID gene therapy trial raised concerns about the safety of insertional mutagenesis inherent to the biology of the retr