A new peptidomimetic scaffold based on 5-(aminomethyl)pyrrole-2-carboxylic acid (1) is developed for the first time and used as a conformationally constrained surrogate of the Gly-DAla dipeptide isostere (2) to prepare peptides 3 and 4.
Development of 2,3-diazabicyclo[2.2.1]heptane as a constrained azapeptide template and its uses in peptidomimetic studies
β Scribed by Tushar K Chakraborty; Animesh Ghosh; A.Ravi Sankar; Ajit C Kunwar
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 146 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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