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Development: Differentiation goes up a Notch

✍ Scribed by Burgess, Darren J.


Book ID
109953372
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
206 KB
Volume
12
Category
Article
ISSN
1471-0056

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Signaling through both the transforming growth factor b (TGFb) superfamily of growth factors and Notch play crucial roles during embryonic pattern formation and cell fate determination. Although both pathways are able to exert similar biological responses in certain cell types, a functional interact