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Development and validation of RP-HPLC-UV method for simultaneous determination of buparvaquone, atenolol, propranolol, quinidine and verapamil: A tool for the standardization of rat in situ intestinal permeability studies

✍ Scribed by Gantala Venkatesh; S. Ramanathan; S.M. Mansor; N.K. Nair; Munavvar Abdul Sattar; Simon L. Croft; V. Navaratnam


Book ID
108189349
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
169 KB
Volume
43
Category
Article
ISSN
0731-7085

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## Abstract A simple and rapid high‐performance liquid chromatographic method was developed and validated for the analysis in rat plasma of BOL‐303225‐A, a new coumarin‐based anti‐inflammatory drug. Liquid–liquid extraction was used for sample preparation. Chromatographic separation was achieved on