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Development and validation of HPLC method for the determination of tobramycin in urine samples post-inhalation using pre-column derivatisation with fluorescein isothiocyanate

✍ Scribed by M. Mashat; H. Chrystyn; B.J. Clark; K.H. Assi


Book ID
108160862
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
719 KB
Volume
869
Category
Article
ISSN
1873-376X

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## Abstract A new rapid, sensitive and validated HPLC method has been developed for the determination of methylxanthines and their metabolites in asthmatic patients. The method was initiated by using spiked urine samples on a silica monolithic column as a novel packing material. The mobile phase co