Development and validation of an LC-MS-MS method for determination of methyl kulonate in rat plasma
β Scribed by Zhipeng Deng; Tao Yuan; Shuxiang Cui; Shaochao Liu; Yanying Xie; Qingqiang Yao
- Book ID
- 112013417
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 973 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.1741
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml-1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml-1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and a
A sensitive and specific LC/MS/MS method for the determination of L-hyoscyamine was developed and validated over the linearity range 20-500 pg ml-1 with 1.0 ml of plasma using scopolamine as the internal standard. The API III-Plus LC/MS/MS was operated under the multiple reaction monitoring mode usi