Development and validation of a UPLC/MS method for a nutritional metabolomic study of human plasma
✍ Scribed by Hélène Pereira; Jean-François Martin; Charlotte Joly; Jean-Louis Sébédio; Estelle Pujos-Guillot
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 726 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1573-3882
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## ABSTRACT A highly sensitive, specific and simple LC‐MS/MS method was developed for the simultaneous estimation of dexlansoprazole (DEX) with 50 μL of human plasma using omeprazole as an internal standard (IS). The API‐4000 LC‐MS/MS was operated under multiple reaction‐monitoring mode using elect
A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml-1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml-1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and a
A sensitive and specific LC/MS/MS method for the determination of L-hyoscyamine was developed and validated over the linearity range 20-500 pg ml-1 with 1.0 ml of plasma using scopolamine as the internal standard. The API III-Plus LC/MS/MS was operated under the multiple reaction monitoring mode usi