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Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles

✍ Scribed by José das Neves; Bruno Sarmento; Mansoor M. Amiji; Maria Fernanda Bahia

Book ID: 108189746
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 300 KB
Volume: 52
Category: Article
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2010.01.007

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## Abstract Besides liquid chromatographic (LC)/UV methods adapted to therapeutic drug monitoring, there is still a need for more powerful techniques that can be used for pharmacological research and clinical purposes. We developed an LC method coupled with tandem mass spectrometry (MS/MS) to separ