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Development and validation of a rapid method for the detection of latrunculol A in plasma

✍ Scribed by Jiajiu Shaw; Frederick A. Valeriote; Joseph Media; Tyler A. Johnson; Taro Amagata; Karen Tenney; Phillip Crews

Publisher
Springer
Year
2009
Tongue
English
Weight
110 KB
Volume
396
Category
Article
ISSN
1618-2650

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Development and validation of a rapid high-performance liquid chromatography method for the quantification of exenatide
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The objective was to develop a simple HPLC method to quantify exenatide-a 39 amino acid residue incretin mimetic used in diabetes therapy. To date, only non-validated, sometimes incomplete, gradient methods have been reported in the literature. Isocratic separation was achieved using a C4 column and