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Development and validation of a liquid chromatography/tandem mass spectrometry assay for the quantification of methyl protodioscin in rat plasma: application to a pharmacokinetic study

✍ Scribed by Xiuzhen Cao; Zhihong Yao; Haifeng Chen; Yi Dai; Pinghua Sun; Wencai Ye; Xinsheng Yao


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
212 KB
Volume
22
Category
Article
ISSN
0269-3879

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## Abstract Phenazopyridine hydrochloride is a strong analgesic used in the treatment of urinary tract infections. The aim of the present study was to develop a procedure based on gas chromatography‐mass spectrometry (GC‐MS) for the analysis of phenazopyridine in rat plasma. The method was set up a