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Liquid chromatography/electrospray ionization tandem mass spectrometry for the quantification of mitiglinide in human plasma: validation and its application to pharmacokinetic studies

โœ Scribed by Yan Zhang; Likun Ding; Yun Tian; Jing Yang; Lin Yang; Aidong Wen


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
160 KB
Volume
22
Category
Article
ISSN
0269-3879

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## Abstract A simple, sensitive and rapid highโ€performance liquid chromatography/electrospray ionization tandem mass spectrometry method was developed and validated for the assay of granisetron in human plasma. Following liquidโ€“liquid extraction, the analytes were separated using an isocratic mobil