A simple high-performance liquid chromatographic method for the determination of doxazosin in human plasma was developed and validated. Prazosin was used as internal standard. After extraction twice with ethyl acetate, chromatographic separation of doxazosin in human plasma was carried out using a r
✦ LIBER ✦
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma
✍ Scribed by Joana Sousa; Gilberto Alves; Ana Fortuna; Angelina Pena; Celeste Lino; Amílcar Falcão
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 425 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.1480
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## Abstract Attention has shifted from the treatment of colorectal cancer (CRC) to chemoprevention using aspirin and folic acid as agents capable of preventing the onset of colon cancer. However, no sensitive analytical method exists to simultaneously quantify the two drugs when released from polym