Development and validation of a cell culture based assay for in vitro assessment of anticryptosporidial compounds
β Scribed by M. Najdrowski; A. R. Heckeroth; C. Wackwitz; S. Gawlowska; U. Mackenstedt; D. Kliemt; A. Daugschies
- Book ID
- 106128487
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 148 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1432-1955
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have developed a "test-tube" assay to determine the biological activity of synthetic preparations of human calcitonin (hCT). The method is based on the dosedependent accumulation of cyclic AMP in cell membrane preparations on stimulation with CT. As an unlimited cell source, we used the clonal ce
As mice deficient in a particular gene provide an increasing number of novel in vivo models, in vivo assays that examine immune function are becoming a central issue. We found that the sensitivities of in vivo and in vitro assays are strikingly different. These differences have important implication