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Development and specificities of anti-interferon neutralizing antibodies in patients with chronic hepatitis C treated with pegylated interferon-α

✍ Scribed by C. Scagnolari; S. Trombetti; A. Soldà; M. Milella; G. B. Gaeta; G. Angarano; G. Scotto; N. Caporaso; F. Morisco; R. Cozzolongo; G. Giannelli; M. Fasano; T. Santantonio; G. Antonelli

Book ID
115245906
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
151 KB
Volume
18
Category
Article
ISSN
1198-743X

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Neutralizing antibodies to interferon-α
Neutralizing antibodies to interferon-α and circulating interferon in patients with chronic hepatitis C non-responding to pegylated interferon plus ribavirin re-treated by pegylated interferon-α-2a and ribavirin (ANRS HC16 GAMMATRI substudy*)
✍ Philippe Halfon; Sophie Pérusat; Marc Bourlière; Jean-Pierre Bronowicki; Pascale 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB

## Abstract A lack of antiviral response in patients with chronic hepatitis C treated with pegylated (PEG)‐interferon (IFN)‐α‐2a + ribavirin (RIBA) may be explained by neutralizing antibodies to IFN‐α‐2a. The aim of this study was to assess neutralizing antibodies to IFN‐α‐2a and IFN levels in non‐