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Anti-interferon-α neutralizing antibody is associated with nonresponse to pegylated interferon-α plus ribavirin in chronic hepatitis C

✍ Scribed by F. Matsuda; Y. Torii; H. Enomoto; C. Kuga; N. Aizawa; Y. Iwata; M. Saito; H. Imanishi; S. Shimomura; H. Nakamura; H. Tanaka; H. Iijima; H. Tsutsui; Y. Tanaka; S. Nishiguchi


Book ID
117947771
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
311 KB
Volume
19
Category
Article
ISSN
1352-0504

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Neutralizing antibodies to interferon-α
✍ Philippe Halfon; Sophie Pérusat; Marc Bourlière; Jean-Pierre Bronowicki; Pascale 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB

## Abstract A lack of antiviral response in patients with chronic hepatitis C treated with pegylated (PEG)‐interferon (IFN)‐α‐2a + ribavirin (RIBA) may be explained by neutralizing antibodies to IFN‐α‐2a. The aim of this study was to assess neutralizing antibodies to IFN‐α‐2a and IFN levels in non‐