✦ LIBER ✦

Development and Characterization of a Rapid and Comprehensive Genotyping Assay to Detect the Most Common Variants in Cytochrome P450 2D6

✍ Scribed by Lisa A. Scarlett; Soraya Madani; Danny D. Shen; Rodney J. Y. Ho

Book ID: 110251899
Publisher: Springer US
Year: 2000
Tongue: English
Weight: 224 KB
Volume: 17
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1007585801905

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Changes in the QTc interval after admini

Changes in the QTc interval after administration of flecainide acetate, with and without coadministered Paroxetine, in Relation to Cytochrome P450 2D6 Genotype: Data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects

✍ Kyoung Soo Lim; In-Jin Jang; Bo-Hyung Kim; JaeWoo Kim; Ji-Young Jeon; You-Me Tae 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 133 KB

Validation of higher-throughput high-per

Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes

✍ Inhou Chu; Leonard Favreau; Tony Soares; Chin-chung Lin; Amin A. Nomeir 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 2 views

In the early stage of drug discovery, thousands of new chemical entities (NCEs) may be screened before a single drug candidate can be identified for development. In order to accelerate the drug discovery process, we have developed higher-throughput enzyme assays to evaluate the inhibition of cytochr