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Development and characterization of a monoclonal antibody directed against human telomerase reverse transcriptase (hTERT)

✍ Scribed by Dario Soldateschi; Sara Bravaccini; Brunilde Berti; Alessandra Brogi; Tiziana Benicchi; Claudia Soldatini; Laura Medri; Francesco Fabbri; Franca De Paola; Dino Amadori; Daniele Calistri


Book ID
118471363
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
259 KB
Volume
118
Category
Article
ISSN
0168-1656

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Telomerase extends telomeric repeats at the ends of linear chromosomes, thereby prolonging the replicative capacity of cells. To investigate possible regulatory mechanisms of telomerase, we measured telomerase enzyme activity, human telomerase RNA (hTR) and human telomerase reverse transcriptase (hT