Development and application of siRNA expression vector
β Scribed by Miyagishi, M.; Taira, K.
- Book ID
- 118252435
- Publisher
- Oxford University Press
- Year
- 2002
- Weight
- 161 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0261-3166
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## Abstract To synthesize a lipidβcationic polymer (LCP) containing brassidic acid side chain and to investigate its transfection efficiency and characteristics as a siRNA gene vector. The LCP was chemically synthesized and its nucleic acid binding capacity was determined by gel electrophoresis. He
## Background RNA interference (RNAi) was originally identified as a biological process in which short double-stranded RNA (dsRNA) suppress the expression of genes complimentary to the dsRNA. This cellular intrinsic gene silencing mechanism has subsequently been developed as a useful tool for studi