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Inhibition of simian immunodeficiency virus by foamy virus vectors expressing siRNAs

✍ Scribed by Jeonghae Park; Peter Nadeau; James R. Zucali; Calvin M. Johnson; Ayalew Mergia


Book ID
113946537
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
304 KB
Volume
343
Category
Article
ISSN
0042-6822

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## Background: Human gene therapy vectors based on primate lentiviruses harbour in contrast to oncoretroviruses the risk of vector mobilization by human immunodeficiency viruses (hiv). infection of cells transduced with a lentiviral vector by hiv could lead to packaging of the lentiviral vector rna