Development and Application of Biomedical Titanium Alloys

✍ Scribed by Liqiang Wang, Lai-Chang Zhang

• Publisher: Bentham Science Publishers
• Year: 2018
• Tongue: English
• Leaves: 219
• Category: Library

✦ Synopsis

Titanium and its alloys have been widely used as biomedical implant materials due to their low density, good mechanical properties, superior corrosion resistance and biocompatibility when compared with other metallic biomaterials such as Co–Cr alloys and stainless steels. Recently, β-type titanium alloys have been increasingly considered as excellent implant materials because of the remarkable combination of high strength-to-weight ratio, good fatigue resistance, relatively low Young's modulus, good biocompatibility and high corrosion resistance relative to conventional titanium biomaterials. This book covers recent information about biomedical titanium alloy development and 3D printing. Chapters describe the processing, microstructure, mechanical properties and corrosion properties in detail. Information about the surface modification of titanium alloys for biomedical applications, and manufacturing of titanium alloys by new technologies (such as selective laser melting and electron beam melting), is also presented. Readers will learn about the various types of biomedical titanium alloys, their advantages and disadvantages, their fabrication methods and medical applications. This book is a useful handbook for biomedical engineers, metallurgists and biotechnicians seeking information about titanium-based alloys for biomaterials research and development.

✦ Table of Contents

CONTENTS
PREFACE
List of Contributors
Application of Biomedical Titanium Alloys
Liqiang Wang1, and Lai-Chang Zhang2
INTRODUCTION
Α+Β TITANIUM ALLOYS IN BIOMEDICAL APPLICATIONS
Β TITANIUM ALLOYS FOR BIOMEDICAL APPLICATIONS
Current Development of β Titanium Alloys
Design of β Titanium Alloys
Biocompatibility of β Titanium Alloys
PHASE TRANSFORMATIONS OF TITANIUM ALLOYS IN BIOMEDICAL APPLICATIONS
Ti-Ni Alloys
Ti-Nb Alloys
Current Applications of Phase Transformation
CONCLUSION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Microstructure and Mechanical Properties of TiNbTaZr Titanium Alloy
Liqiang Wang1,, Xueting Wang1 and Lai-Chang Zhang2
INTRODUCTION
TiNi Shape Memory Alloy
Biomedical β Titanium Alloy
Elements Design for New Generation of β Titanium Alloy
The Mechanical Properties of β Titanium Alloys
MATERIAL PREPARATION AND EXPERIMENTAL METHOD
Material Preparation
Experiment Equipments and Analysis Methods
Calculation of β Phase Transition Point
Martensite Start Transformation Point (Ms)
INFLUENCE OF DIRECT AND CROSS ROLLING ON MARTENSITE TRANSFORMATION AND MECHANICAL PROPERTIES
Specimen Preparation
Martensite Transformation in Direct Rolling
Martensite Morphology During Direct Rolling Process
Martensite Transformation During Cross Rolling Process
Martensite Morphology During Cross Rolling Process
Strain-induced Martensite Transformation
TEM Analysis of Direct-Rolled Structure
Mechanical Properties of Direct-Rolled Specimen
Mechanical Properties of Cross-Rolled Specimen
SHAPE MEMORY EFFECT OF TI-35NB-3ZR-2TA ALLOY
CONCLUSIONS
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Microstructure and Mechanical Properties of Beta Type Ti-Fe Based Alloys
Lai-Chang Zhang1, and Liqiang Wang2
INTRODUCTION
TI-FE-TA ALLOYS
TI-FE-NB ALLOYS
TI-FE BASED ALLOYS WITH MULTIPLE LENGTH-SCALE PHASES
CONCLUDING REMARKS
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Selective Laser Melting of Titanium Alloys: Processing, Microstructure and Properties
Lai-Chang Zhang1, and Liqiang Wang2
INTRODUCTION
SLM CHARACTERISTICS AND PROCESSING PARAMETERS
Process Overview
Processing Parameters Involved
SLM OF SOLID TITANIUM ALLOYS
SLM of α-type CP-Ti
SLM of (α+β)-type Titanium Alloys
SLM of β-type Titanium Alloy
SLM OF POROUS TITANIUM STRUCTURES
CONCLUDING REMARKS
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Electron Beam Melting of Porous Titanium Alloys: Microstructure and Mechanical Behavior
Lai-Chang Zhang1,, Yujing Liu1 and Liqiang Wang2
INTRODUCTION
MANUFACTURING PROCESS
Defect and Surface Roughness Generation
MECHANICAL PROPERTIES OF POROUS STRUCTURES
Super-elasticity
Fatigue Properties
Fatigue Crack Morphology and Deflection
COMPARISON OF FATIGUE BETWEEN TI2448 AND TI6-AL-4V POROUS STRUCTURES
CONCLUDING REMARKS
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Preparation, Microstructure and Mechanical Properties of NiTi-Nb Porous Titanium Alloy
Liqiang Wang1,, Wei Huang1, Wei Zhang1 and Lai-Chang Zhang2
INTRODUCTION
Shape Memory Alloy
NiTi and NiTiNb Alloy
Phase Transition of NiTi Alloy
NiTi Alloy Properties
(1) Shape Memory Effect
(2) Superelastic Performance
(3) Biocompatibility
NiTi alloy Biomedical Applications
Research About NiTi / NiTi-Nb Alloys
Meaning and Content of This Research Work
PREPARATION AND ANALYSIS OF MATERIALS
Materials Preparation
Experimental Materials
Frame Design
Sintering Process
Analysis Test Methods
Metallographic Microscope
Energy Dispersive Spectrometer
Nanoindentation Test
MICROSTRUCTURE AND MECHANICAL PROPERTIES OF A SINTERED NITI/NITI-NB ALLOY
Experimental Results and Analysis
Characterization of Sintered Metallographic Microstructure
Diffused Layer Scanning
Microstructure Phase and Elemental Composition
CONCLUSIONS
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Surface Modification of Biomedical Titanium Alloys
Zihao Ding1, Liqiang Wang1,, Chengjian Zhang1 and Lai-Chang Zhang2
INTRODUCTION
MATERIALS AND METHODS
Materials and FSP System
Microstructure Observation and Composition Analysis
Nanoindentation
In Vitro Biocompatibility Test
(1) Cytotoxicity Test
(2) Cell Culture
(3) Cell Adhesion
(4) Cell Proliferation
(5) Alkaline Phosphatase Activity
(6) Mineralization Assay
Corrosion Resistance
RESULTS AND DISCUSSIONS
Microstructure
Microhardness
Biocompatibility Test
(1) Cytotoxicity Assay
(2) Cell Adhesion Assay
(3) Cell Proliferation Assay
Corrosion Behavior
CONCLUSION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Corrosion Behavior of Selective Laser Melted Titanium Alloys
Lai-Chang Zhang1,, Junxi Zhang2 and Liqiang Wang3
INTRODUCTION
CORROSION BEHAVIOR OF SLM-PRODUCED TI-6AL-4V
CORROSION BEHAVIOR OF SLM-PRODUCED TI-6AL-4V AFTER HEAT TREATMENT
CORROSION BEHAVIOR OF SLM-PRODUCED TITANINUM COMPOSITE
CONCLUDING REMARKS
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
SUBJECT INDEX