Deuterium isotope effects on degradation of hydrocortisone in aqueous solution
โ Scribed by Ian H. Pitman; T. Higuchi; M. Alton; R. Wiley
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 342 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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## Abstract The proton transfer equilibrium in a series of double Schiff base derivatives of __trans__โ1,2โdiaminocyclohexane in solution and the solid state was studied by means of ^15^N NMR spectroscopy and analysis of the deuterium isotope effect on the chemical shifts ฮ^15^N(D). The presence of