Deuterium-induced 13C nuclear magnetic resonance isotope shifts and 13C2H couplings for signal assignments and determination of deuteration site in cyclooctanone

✍ Scribed by Slobodan Milosavljević; Dragoslav Jeremić; Mihailo Lj. Mihailović; Felix W. Wehrli

• Publisher: John Wiley and Sons
• Year: 1981
• Tongue: English
• Weight: 158 KB
• Volume: 17
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/mrc.1270170415

✦ Synopsis

Abstract

Unambiguous signal assignments in the ^13^C spectra of monodeuterated cyclooctanones derived from the lead tetraacetate or silver oxide/bromine oxidations of the corresponding 1‐monodeutero‐alcohols have been obtained from deuterium‐induced ^13^C isotope shifts and geminal and vicinal ^13^C^2^H spin‐spin coupling constants. The label in the ketones is shown to be in position 5.