Deuteration of proteins and polyamides in deuterium oxide vapor
β Scribed by Jeffries, R.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1964
- Tongue
- English
- Weight
- 555 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0449-2951
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π SIMILAR VOLUMES
A number of phenols and aromatic ethers were dcuterated in positions ortho and para to the phenolic groups using BF, etherate followed by quenching with Na,CO, in D,O. This method involves mild reaction conditions and should have wide applicability in the isotopic labeling of these compounds.
## Abstract Aromatic compounds bearing an __ortho__βdirecting substituent may be deuterated by exchange with deuterium oxide in the presence of a range of cyclooctaβ1,5βdienyliridium(I)1,3βdionate catalysts. The exchange takes place in several dipolar aprotic solvents and is directly applicable to