Determining causality and consequence of expression quantitative trait loci
β Scribed by Battle, A.; Montgomery, S. B.
- Book ID
- 121841885
- Publisher
- Springer
- Year
- 2014
- Tongue
- English
- Weight
- 537 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
As compared to classical, fixed sample size techniques, simulation studies showed that a proposed sequential sampling procedure can provide a substantial decrease (up to 50%, in some cases) in the mean sample size required for the detection of linkage between marker loci and quantitative trait loci.
The cost of experiments aimed at determining linkage between marker loci and quantitative trait loci (QTL) was investigated as a function of marker spacing and number of individuals scored. It was found that for a variety of experimental designs, fairly wide marker spacings (ca. 50 cM) are optimum o