Determination of Xanthine Dehydrogenase mRNA by a Reverse Transcription-Coupled Competitive Quantitative Polymerase Chain Reaction Assay: Regulation in Rat Endothelial Cells by Hypoxia and Hyperoxia

Regulation of GABAA receptor subunit mRN

Regulation of GABAA receptor subunit mRNA expression by the pesticide dieldrin in embryonic brainstem cultures: A quantitative, competitive reverse transcription-polymerase chain reaction study

✍ Jiangping Liu; A. Leslie Morrow; Leslie L. Devaud; Dennis R. Grayson; Jean M. La 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB 👁 2 views

Cyclodiene organochlorine pesticides, such as dieldrin, inhibit ␥-aminobutyric acid (GABA)ergic neurotransmission by blocking the Cl ؊ channel of GABA A receptors. This action may make the developing nervous system especially vulnerable to these neurotoxins, which could interfere with the trophic ac