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Determination of transcription start sites in the human estrogen receptor gene and identification of a novel, tissue-specific, estrogen receptor-mRNA isoform

✍ Scribed by K. Grandien


Book ID
116122730
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
673 KB
Volume
116
Category
Article
ISSN
0303-7207

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## Abstract Estrogen (17β‐estradiol, E2) plays pivotal roles in the function and maintenance of the skeleton, including the bone‐forming osteoblasts (OBs). The functions of E2 are largely mediated through two distinct estrogen receptor isoforms, ERΞ± and ERΞ², both of which are expressed in OBs. The