A study of the applicability of circular dichroism (CD) for the determination of drug levels in human serum is described and a new method for the quantitative determination of optically active absorbing drugs having Cotton effects at wavelengths about 250 nm in human serum and/or plasma is proposed.
Determination of the Type of Linkage in Disaccharides by Measurement of Circular Dichroism
โ Scribed by Priv.-Doz. Dr. Wolfgang Voelter; Gisela Kuhfittig; Prof. Dr. Ernst Bayer
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 196 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0044-8249
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The absolute configuration of the (ร)-enantiomer of mirtazapine was determined by means of vibrational circular dichroism (VCD). The observed VCD of (ร)-mirtazapine showed excellent correlation with the calculated VCD of the (R)-enantiomer. This is in agreement with the absolute configuration as det
## Abstract Vibrational circular dichroism (VCD) spectroscopy was used to investigate the solution conformations of cyclosporins A, C, D, G, and H in CDCl~3~, in the amide I and NH/OHโstretching regions, and their corresponding magnesium complexes in CD~3~CN, in the amide I region. VCD spectra are