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Determination of the sequential degradation of myelin proteins by macrophages

โœ Scribed by Annette van der Goes; Wiebe Boorsma; Karin Hoekstra; Lisette Montagne; Corline J.A. de Groot; Christine D. Dijkstra

Book ID
113729513
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
339 KB
Volume
161
Category
Article
ISSN
0165-5728

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Degradation of myelin basic protein by c
Degradation of myelin basic protein by cerebrospinal fluid: Preservation of antigenic determinants under physiological conditions
โœ Dr Ellsworth C. Alvord Jr; Sarka Hruby; Linda R. Sires ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 844 KB

## Abstract Cerebrospinal fluid contains several proteolytic enzymes that can degrade myelin basic protein (BP) under physiological conditions into peptide fragments of various sizes which still contain antigenic determinants capable of binding antibodies to BP. These enzymes are optimally active i