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Determination of sennoside A and B in the pharmaceutical preparation Otsuji-to using ion-pair high-performance liquid chromatography with column switching

โœ Scribed by Toshiyuki Oshima; Fusayoshi Hirayama; Mitsuhiro Masuda; Tadao Maruta; Kazuhiko Sagara; Taku Mizutani; He Li-Yi; Tong Yu-Yi; Chen Yu-Heng; Hideji Itokawa


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
364 KB
Volume
585
Category
Article
ISSN
1873-3778

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Low Picogram Determination of Ro 48-6791
โœ M. Zell; C. Husser; G. Hopfgartner ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 263 KB ๐Ÿ‘ 2 views

A coupled liquid chromatography/tandem mass spectrometry assay was developed for simultaneous determination of Ro 48-6791 and its secondary amine metabolite in human plasma samples with a quantification limit for both compounds of 1 pg/mL using a 1 mL plasma aliquot. The method exploits the enhanced