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Determination of risperidone and its major metabolite 9-hydroxyrisperidone in human plasma by reversed-phase liquid chromatography with ultraviolet detection

✍ Scribed by Angela Avenoso; Gabriella Facciolà; Monica Salemi; Edoardo Spina


Book ID
108447633
Publisher
Elsevier Science
Year
2000
Weight
232 KB
Volume
746
Category
Article
ISSN
0378-4347

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A method for the determination of bupropion and its three major basic metabolites in plasma is described. Following an extraction from alkaline plasma into 1.5% v/v isoamyl alcohol in n-heptane, a portion of the acid-backwashed extract was injected onto a column packed with trimethylsilyl reverse-ph