𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Determination of promethazine by its inhibition of the chemiluminescence of the luminol—hydrogen peroxide—chromium(III) system

✍ Scribed by Abdulrahman A. Alwarthan; Saad A. Al-Tamrah; Akel A. Akel

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
486 KB
Volume
282
Category
Article
ISSN
0003-2670

No coin nor oath required. For personal study only.

✦ Synopsis

The huninol-H,O,-metal ion system has been widely used in chemical and biological analysis. A method is described for the determination of promethazine based on its inhibition of the intensity of chemiluminescence from the luminol system. The method is sensitive, convenient and simple with a detection limit of 3 x lOA M. The R.S.D. at 1 X 10m5 M promethazine is 1.3% (ten replicates). The method was applied successfully to the analysis of various commercially available dosage forms containing promethazine. The results obtained for the assay of commercial preparations compared well with those obtained by the offkial method and showed good accuracy and precision.

📜 SIMILAR VOLUMES

Flow system for the automatic screening
Flow system for the automatic screening of the effect of phenolic compounds on the luminol–hydrogen peroxide–peroxidase chemiluminescence system
✍ André R. T. S. Araujo; Fernando Maya; M. Lúcia M. F. S. Saraiva; José L. F. C. L 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 411 KB

## ABSTRACT In this work, an automated flow‐based procedure for the screening of the effect of the different phenolic compounds on the chemiluminescence (CL) luminol–hydrogen peroxide–horseradish peroxidase (HRP) system is presented. This procedure involves the combination of multisyringe flow inje

A novel chemiluminescent flow injection
A novel chemiluminescent flow injection analysis of trace amounts of rutin by its inhibition of the luminol–hydrogen peroxide reaction catalyzed by tetrasulfonated colbalt phthalocyanine
✍ Qiyong Zhu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 278 KB 👁 2 views

## Abstract Based on the inhibition effect of rutin on the luminol–hydrogen peroxide chemiluminescence (CL) system catalyzed by tetrasulfonated colbalt phthalocyanine (CoTSPc), a sensitive flow‐injection CL method has been developed for the determination of rutin. The CL reaction mechanism was care

Chemiluminescence intensities and spectr
Chemiluminescence intensities and spectra of luminol oxidation by sodium hypochlorite in the presence of hydrogen peroxide
✍ Arnhold, J. ;Mueller, S. ;Arnold, K. ;Grimm, E. 📂 Article 📅 1991 🏛 John Wiley and Sons ⚖ 321 KB 👁 2 views

Hydrogen peroxide amplifies the chemiluminescence in the odixation of luminol by sodium hypochlorite. A linear relationship between concentration of hydrogen peroxide and light intensity was found in the concentration range 5 x 10-\*-7.5 x mol/l. At 7.5 x l o -' mol/l H,Oz the chemiluminescence is a

Inhibition of the system luminol-H2O2-Fe
Inhibition of the system luminol-H2O2-Fe(CN)63− chemiluminescence by the Mn(II) indirect determination of isoniazid in a pharmaceutical formulation
✍ Alapont, A. Gregorio ;Giménez, E. Aurechia ;Zamora, L. Lahuerta ;Calatayud, J. M 📂 Article 📅 1998 🏛 John Wiley and Sons ⚖ 118 KB 👁 2 views

A flow injection procedure for the indirect chemiluminescent determination of isoniazid is proposed. The method is performed in a flow-injection manifold provided with a solid-phase reactor. The reactor was made from manganese dioxide physically entrapped by polymerization; the redox reaction isonia