𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Determination of piribedil in biological materials by gas—liquid chromatography—mass fragmentography

✍ Scribed by R. Fanelli; A. Frigerio

Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
338 KB
Volume
93
Category
Article
ISSN
1873-3778

No coin nor oath required. For personal study only.

✦ Synopsis

A sensitive and specific method for the quantitative determination of piribedil in brain tissue and plasma is described. After extraction, piribedil is detected by gas-liquid chromatography using a flame ionization detector or the mass fragmentographic technique, and these two procedures allow 250 and 10 ng/ml or rig/g,, respectively, of piribedil present in biological samples to be determined.

📜 SIMILAR VOLUMES

Quantitative assay of diclofenac in biol
Quantitative assay of diclofenac in biological material by gas—liquid chromatography
✍ U.P. Geiger; P.H. Degen; A. Sioufi 📂 Article 📅 1975 🏛 Elsevier Science 🌐 English ⚖ 405 KB

Diclofenac and an internal standard are isolated from biological samples by acid-specific extraction and converted into the corresponding indolones with 0.5% sulphuric acid in 2,2,2-trifluorethanol. The neutral derivatives are isolated by solvent extraction and subjected to gas-liquid chromatography

Determination of bufuralol and its metab
Determination of bufuralol and its metabolites in plasma by mass fragmentography and by gas chromatography with electron capture detection
✍ R. J. Francis; P. B. East; S. J. McLaren; J. Larman 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 375 KB 👁 2 views

A sensitive method for the simulataneous determination of bufuralol and its pharmacologically active metabolites in huamn plasma is described. The O-timethylsilyl,N-trifluoroacetyl derivatives are assayed by mass fragmentography. Sensitivity is 1 ng 76(-1) plasma for bufaralol and about 250 pg ml(-1