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Determination of piretanide and furosemide in pharmaceuticals and human urine by high-performance liquid chromatography with amperometric detection

✍ Scribed by M.B. Barroso; R.M. Jiménez; R.M. Alonso; E. Ortiz

Publisher
Elsevier Science
Year
1996
Weight
588 KB
Volume
675
Category
Article
ISSN
0378-4347

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## Abstract A simple, specific and sensitive HPLC method has been developed for the determination of metoprolol in human plasma and urine. Separation of metoprolol and atenolol (internal standard) was achieved on an Ace C~18~ column (5 μm, 250 mm×4.6 mm id) using fluorescence detection with λ~ex~=2