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Determination of phenylephrine with a modified carbon paste electrode

✍ Scribed by J.C. Perlado; A. Zapardiel; E. Bermejo; J.A. Pérez; L. Hernández

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
649 KB
Volume
305
Category
Article
ISSN
0003-2670

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✦ Synopsis

An anodic stripping voltammetric method for determination of phenylephrine with a modified carbon paste electrode is developed. The modified carbon paste electrode was prepared with carbon paste mixed with a cation exchange resin containing the functional group CO,Na. Linear scan voltammetry was used for the electrochemical measurements. The experimental conditions for preconcentration and measurement steps have been optimized in order to attain the optimum analytical signal. In 0.1 M hydrochloric acid the drug shows a well defined oxidation peak at 1.07 V (vs. Ag/AgC1/3 M KCI). A procedure for determining phenylephrine in urine is also described.

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