Determination of Nitrendipine with β-Cyclodextrin Modified Carbon Paste Electrode

✍ Scribed by C. Yáñez; L. J. Núñez-Vergara; J. A. Squella

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 83 KB
• Volume: 14
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/1521-4109(200204)14:7/8<559::aid-elan559>3.0.co;2-0

✦ Synopsis

Carbon paste electrodes modified with b-cyclodextrin have been investigated for voltammetric determination of nitrendipine. The immobilization of the b-cyclodextrin on the carbon paste leads to a modification of the electrode surface that causes a significant increase in the peak current of the nitrendipine reduction, probably due to formation of an inclusion complex between b-cyclodextrin and nitrendipine. This property was used with analytical purposes by developing a stripping differential pulse voltammetric (SDPV) method to determine nitrendipine.